genetic familial mutations
498 articles
ASCO 2023: Pancreatic Cancer Research Update
The pancreatic cancer research reports from ASCO 2023 focused on different chemotherapy combinations, including immunotherapy.
Newly Discovered Protein Complex in RAS Pathway May Provide a Treatment Target
Dr. Andrew Aguirre and other researchers from Dana-Farber and the Broad Institute are looking at the RAS pathway for a new target.
Precursors to Pancreatic Cancer: Are There Any Signs to Watch Out For?
Dr. Venkata Akshintala outlines some of the precursors to pancreatic cancer that people should look out for.
ASCO Annual Conference: Highlights in Pancreatic Cancer Research
Dr. Allyson Ocean reviews some of the latest pancreatic cancer research results, including new treatments for some patients.
Testing a Signal-Inhibiting Drug on Tumors with Specific Mutations
A new drug for certain tumor mutations is being tested in a type of clinical trial called a basket trial, which matches tumor genetics and drugs.
Tailoring My Treatment to My Tumor Genetics
After diagnosis with pancreatic cancer, Sharon Simone had her tumor analyzed. The report on her tumor genetics determined her treatment.
A Genetic Mutation Aids My Treatment
Malcolm Robertson carries the BRCA2 mutation, so when he was diagnosed with pancreatic cancer, platinum-based chemo was part of his treatment.
Genetic Testing Leads Me to a PARP Inhibitor Trial
Harvey Parker had genetic testing as part of his initial pancreatic cancer treatment. The BRCA2 mutation led him to a PARP inhibitor clinical trial.
BRCA Mutation Determines My Pancreatic Cancer Treatment
Chris Treubert started with one type of chemotherapy but when the results of genetic testing showed a BRCA mutation he changed treatment.
Questions to Ask Before You Begin Chemotherapy
Do you want to better understand your pancreatic cancer treatment? Dr. Andrew Hendifar outlines important questions to ask before starting chemotherapy.
My BRCA2 Mutation Turned Out to Be Both the Curse and the Cure
Sharon Seibel knew she had the BRCA2 mutation but was unaware of the link to pancreatic cancer. Her chemotherapy was one for BRCA carriers.
Which Is the Best Screening Method for Pancreatic Cancer?
Dr. Aimee Lucas outlines the pros and cons of various screening methods that can be used for pancreatic cancer, and who should be using them.
Targeting the Undruggable KRAS Protein
Dr. Shubham Pant is focusing his research on effective treatments for the KRAS mutation, found in 90% of pancreatic cancers.
Highlights from the 2025 AACR Annual Meeting
Drugs to target KRAS, better imaging for earlier detection, and cachexia prediction are among the research highlights from AACR 2025.
Extensive Family History and Genetic Testing Leads to Early Detection
Sidney Levinson and his doctor were aware of his BRCA1/2 mutations so when an MRI was recommended for screening, Sidney did it.