Risk Factors

437 articles

Treatments
July 24, 2019 • 7 Min

Prognosis: More Than Numbers in Pancreatic Cancer

What is pancreatic cancer prognosis? Dr. Joshua Lakin of Harvard explains how prognosis works, and ways to possibly defy the odds when facing a slow recovery.

Survivor Stories
March 28, 2017 • 4 Min

Tailoring My Treatment to My Tumor Genetics

After diagnosis with pancreatic cancer, Sharon Simone had her tumor analyzed. The report on her tumor genetics determined her treatment.

Survivor Stories
July 19, 2017 • 5 Min

Hope and a Chance to Fight

Irwin Greenblatt just wanted a chance, so after Whipple surgery he agreed to join a chemotherapy clinical trial. His wife Audrey tells their story.

Survivor Stories
October 1, 2019 • 9 Min

A Second Opinion Leads to a New Treatment Plan

Brad Kerr changed his pancreatic cancer treatment plan after getting a second opinion, and had neoadjuvant chemotherapy before his Whipple.

Research
July 16, 2021 • 2 Min

Identifying Biomarkers for Early Detection of Pancreatic Cancer

A clinical trial for at-risk people is looking for biomarkers that can indicate pancreatic cancer is growing.

Research
July 28, 2016 • 6 Min

Novel Drug Therapy Kills Pancreatic Cancer Cells by Reducing Levels of Antioxidants

New research finds that reducing antioxidants can help kill pancreatic cancer cells, suggesting a new direction for treatment.

Research
January 24, 2016 • 5 Min

Precision Promise Places Patients at Center of Research

Dr. Diane Simeone explains the different approach to pancreatic cancer clinical trials taken by the Precision Promise program.

Research
March 31, 2017 • 4 Min

Clinical Trial of Immunotherapy Plus Sunshine Vitamin May Help in Pancreatic Cancer Fight

Can vitamin D make it easier for chemotherapy drugs to reach the pancreatic cancer tumor? A clinical trial is testing this idea.

Research
May 25, 2018 • 4 Min

The Promise of Organoids

Dr. Brian Wolpin explains how organoids are being used to develop personalized treatment for pancreatic cancer patients.

Research
June 21, 2018 • 3 Min

Multicenter Trial Focuses on Neoadjuvant Treatment for Borderline Resectable and Locally Advanced Disease

Dr. David Ryan outlines a new trial for pre-surgical pancreatic cancer treatment combining a blood pressure drug, immunotherapy, standard care and SBRT.

Research
March 13, 2019 • 5 Min

Pancreatic Cancer Exceptional Responders and the Immune System Link

Dr. Vinod Balachandran looks at the immune system of exceptional responders–patients who respond extremely well to chemotherapy–for treatment clues.

Research
May 15, 2019 • 5 Min

Representing Genetic and Clinical Diversity in Pancreatic Cancer

Dr. Kentaro Sudo explores the possible causes for different responses to drugs among ethnic groups, pointing to the need for clinical diversity in trials.

Research
September 10, 2019 • 4 Min

CAR T Cell Trial Targets Mesothelin

In an immunotherapy clinical trial, Dr. Mark O’Hara is using CAR T cells to attack mesothelin-expressing tumor cells in pancreatic cancer.

Research
April 16, 2020 • 5 Min

Targeting Mutant KRAS with Immunotherapy

Dr. Beatriz Carreno explains how her team is targeting the KRAS mutation with a pancreatic cancer vaccine to make the immune system work against cancer.

Research
March 31, 2022 • 7 Min

New Trial to Find Biomarkers to Guide Treatment

Drs. Jennifer Knox and Elizabeth Jaffee lead the PASS-01 trial using biomarkers and other measures to choose individualized treatment.