Managing Your Care

619 articles

A confocal microscopy image of a fibroblast showing the football-shaped nucleus (blue), dots of mitochondria (red), and wispy strands of the actin cytoskeleton (green), all against a black background
Research
September 27, 2016 • 2 Min

High-Dose Focused Radiation after Surgical Removal of Pancreatic Tumors

A clinical trial looks at the effectiveness of stereotactic body radiation therapy in killing cancer cells in the margins after pancreatic tumor removal.

Microscope image of four pancreatic cells with pinkish edges and green centers, against a dark background
Research
October 10, 2016 • 2 Min

A Novel Combination to Slow Pancreas Tumors that Cannot Be Surgically Removed

Can a combination of standard drugs, a PARP inhibitor, and intensity modulated radiation therapy to slow pancreatic tumor growth?

Four transparent oblong orange pills and five round white pills on an orange background
Research
October 31, 2016 • 2 Min

Using a Vitamin to Make Low-Dose Chemotherapy More Effective

A clinical trial compares the effectiveness of low-dose continuous chemotherapy with and without high doses of vitamin C.

microscope slide of Pancreas cross section embedded in paraffin wax, stained lavender, 10x magnification,
Research
November 11, 2016 • 2 Min

Immunotherapy to Help Shrink Pancreatic Tumors for Surgery

Researchers are looking at adding checkpoint drugs–a type of immunotherapy–to standard chemoradiation to shrink pancreatic cancer for surgery.

Image of DNA on a blue background showing blue columns of different lengths broken up by bands of red, green, aqua, and lighter blue.
Research
November 28, 2016 • 2 Min

Testing the Effectiveness of Radiation and Standard Treatment

A clinical trial compares FOLFIRINOX plus stereotactic body radiation therapy (SBRT) with just FOLFIRINOX for pancreatic cancer that has spread locally.

Abstract black and white image of laboratory equipment and tubes
Research
December 9, 2016 • 2 Min

Muting Chemical Signals to Slow or Stop the Spread of Pancreatic Cancer

A clinical trial tests a drug that turns off chemical signals in the body that promote the growth of tumors and the spread of pancreatic cancer.

against a dark blue background, transparent tubes in orange, lighter blue, red, and clear, indicate different aspects of cell transport. The image was created through an electron microscope.
Research
December 22, 2016 • 2 Min

A New Approach to Treating Some Advanced Pancreatic Cancer Patients

A clinical trial uses PEGPH20, a synthetic form of a human enzyme, to make treatment more effective in pancreatic cancer patients with high tumor pressure.

Close-up image of the top of a centrifuge, over the central axis
Research
January 2, 2017 • 2 Min

Testing Targeted Immunotherapy Against Pancreatic Cancer

Targeted immunotherapy is the focus of a clinical trial that tests the drug ibrutinib, approved for leukemia treatment, against pancreatic cancer.

Image of a yellow and gold metal circle with wires across the center, in an abstract geometic pattern.
Research
January 27, 2017 • 2 Min

Electrical Pulses to Destroy Pancreatic Cancer Cells

A clinical trial looks the effectiveness of NanoKnife surgery on pancreatic cancer tumors that cannot be removed by traditional surgery.

Four test tubes with open caps in a blue rack; liquid is being poured into one tube.
Research
February 9, 2017 • 2 Min

Testing Standard Treatment Plus an Antibody to Shrink Pancreatic Tumors

Researchers are testing whether adding a monoclonal antibody to standard chemotherapy will make locally advanced pancreatic cancer qualify for surgery.

photo of yellow pills in silver bubble packets
Research
March 10, 2017 • 2 Min

Maintenance Chemotherapy for Stable Metastatic Pancreatic Cancer

A clinical trial tests the diabetes drug metformin and transplant rejection preventative rapamycin to act as maintenance chemotherapy for pancreatic cancer.

Microscope image of a cross section of circular pancreas cells with lighter centers, stained pink
Research
March 23, 2017 • 2 Min

Two Types of Immunotherapy for Surgically Removable Pancreatic Cancer

A clinical trial compares the effectiveness of two different types of immunotherapy with standard treatment after pancreatic cancer surgery.

Black and white photo of clear plastic disks stacked randomly
Research
April 5, 2017 • 2 Min

Comparing Chemotherapy and Radiation Regimens to Prevent Recurrence of Pancreatic Cancer

A clinical trial compares standard chemotherapy with gemcitabine to the combination of chemotherapy with capecitabine and radiation.

Microscope image of pancreatic cells in purple and teal on a dark background
Research
April 18, 2017 • 2 Min

Testing a Signal-Inhibiting Drug on Tumors with Specific Mutations

A new drug for certain tumor mutations is being tested in a type of clinical trial called a basket trial, which matches tumor genetics and drugs.

Image of DNA analysis showing a series of darker and lighter orange-colored columns with thin horizontal red, yellow, white, and orange stripes indicating different genes
Research
June 2, 2017 • 2 Min

Focusing on a Drug that Treats Specific Tumor Mutations

A clinical trial tests a signal-inhibiting drug for lung cancers with specific genetic mutations on gastrointestinal cancers with the same tumor mutations.