Immunotherapy
What is immunotherapy and how can it help those that have been diagnosed with pancreatic cancer? Learn the ins and outs of immunotherapy-related treatments, clinical trials, and vaccines, and how they can be integrated into your treatment plan.
61 Articles
Testing the Effectiveness of Immunotherapy Added to a New Drug Combination
Researchers are testing a drug combination that adds immunotherapy to standard drugs used to treat pancreatic cancer and an antimalarial drug.
Immunology Researchers Solve a Mystery of Metastasis
Physician and researcher Douglas Fearon and his lab have a possible explanation for how cancer cells metastasize, and the role surgery may play in this process.
Testing Immunotherapy for Safety Before and After Pancreatic Cancer Removal
Researchers are testing a new monoclonal antibody to see if it helps patients with pancreatic tumors that can be surgically removed.
Collaborative Multi-Center Immunotherapy Trial Targets CD40 and PD-1
Dr. Mark O’Hara outlines a collaborative clinical trial of two immunotherapy agents–a checkpoint inhibitor and a monoclonal antibody–plus standard chemotherapy.
Immunotherapy for Pancreatic Neuroendocrine Tumors
A clinical trial combines the immunotherapy drug pembrolizumab with lanreotide, a drug typically used to treat pancreatic neuroendocrine tumors.
The Stroma Presents Challenges and Treatment Opportunities
Dr. Elizabeth Jaffee explains how researchers are approaching penetrating the fibrous stroma around pancreatic tumors, which has long challenged treatment.
Neoantigens Provide New Hope for Pancreatic Cancer Treatments
Vinod Balachandran’s team identified increased T cells in the tumors of long-term pancreatic cancer survivors, with a role for neoantigens in immunotherapy.
Overcoming Challenges to Vaccine Immunotherapy
Dr. Elizabeth Jaffee explains the challenges facing the scientists developing vaccine-based immunotherapy for pancreatic cancer.
More Research Needed for Pancreatic Cancer Immunotherapy
Dr. Luis Diaz provides a status check for immunotherapy treatments for pancreatic cancer, including an explanation of different types.
An Immunotherapy Game Changer
Immunotherapy with Keytruda (pembrolizumab) is approved for use in cancer patients with certain genetic defects in their tumors.
Two Types of Immunotherapy for Surgically Removable Pancreatic Cancer
A clinical trial compares the effectiveness of two different types of immunotherapy with standard treatment after pancreatic cancer surgery.
Testing Targeted Immunotherapy Against Pancreatic Cancer
Targeted immunotherapy is the focus of a clinical trial that tests the drug ibrutinib, approved for leukemia treatment, against pancreatic cancer.
Immunotherapy Treatments Provide Hope to Pancreatic Cancer Patients
Dr. Robert Vonderheide of the Abramson Cancer Center at the University of Pennsylvania describes immunotherapy trials for pancreatic cancer.
Immunotherapy to Help Shrink Pancreatic Tumors for Surgery
Researchers are looking at adding checkpoint drugs–a type of immunotherapy–to standard chemoradiation to shrink pancreatic cancer for surgery.
Putting the Immune System on the Offensive
A discussion of immunology in cancer treatment, focusing on the work of Elizabeth Jaffe, M.D., and her cancer vaccine and checkpoint inhibitors.