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photo of Lynne Holcomb, pancreatic cancer patient, in a car

I’ll Never Stop Fighting

When Lynne Holcomb was diagnosed with stage IV pancreatic cancer, she kept fighting through treatment and made it onto a clinical trial.

Portrait photo of Dr. Ryan Nipp

New Study Focuses On Supportive Oncology Care At Home

For some newly diagnosed patients with borderline resectable tumors or locally advanced disease, neoadjuvant therapy is proving to be a game-changer. One such neoadjuvant approach uses FOLFIRINOX, a combination of the drugs leucovorin, fluorouracil, irinotecan, and oxaliplatin. Preoperative treatment with this regimen shows the potential to improve the odds of an R0 resection, meaning no…

Precancerous pancreatic cells in mice

A New Drug to Target Cancer Cell Enzymes

This trial remains active but is no longer recruiting participants. In patients with metastatic pancreatic cancer, researchers are comparing FOLFIRINOX, the standard treatment, with FOLFIRINOX plus CPI-613, a new drug that works on enzymes involved in cancer cell energy metabolism. Target: Enzymes Mitochondria are components within a cell that are responsible for generating the energy…

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