Research
535 articles
Collaborative Multi-Center Immunotherapy Trial Targets CD40 and PD-1
Dr. Mark O’Hara outlines a collaborative clinical trial of two immunotherapy agents–a checkpoint inhibitor and a monoclonal antibody–plus standard chemotherapy.
Two New Immunotherapy Trials Aim to Make Therapy More Effective
Two clinical trials in the Lustgarten Foundation’s Clinical Accelerator are testing different combinations of immunotherapy.
Disappointing Results of a Phase II Trial Using Angiogenesis Inhibitor
Dr. Tanios Bekaii-Saab reports on the disappointing results of a trial combining an angiogenesis inhibitor and mFOLFIRINOX.
Blood-Based Test Predicts What Drugs May Work Best
Dr. Kenneth Yu is testing a blood-based assay that looks at which types of chemotherapies will work best for each pancreatic cancer patient.
Targeting Mutant KRAS with Immunotherapy
Dr. Beatriz Carreno explains how her team is targeting the KRAS mutation with a pancreatic cancer vaccine to make the immune system work against cancer.
New Study Combines Checkpoint Inhibitors with Radiation Therapy to Boost Immune Response
Dr. Theodore Hong combines checkpoint inhibitors–a type of immunotherapy–with radiation to boost the immune system in pancreatic cancer treatment.
GENERATE Study Aims to Improve Genetic Testing and Prevention for Pancreatic Cancer
Dr. Sapna Syngal outlines the GENERATE study, which aims to help families with a risk for pancreatic cancer by providing genetic testing.
New Biopsy Shows Promise For Pancreatic Cancer Patients
Trovagene is developing a liquid biopsy for pancreatic cancer patients, to allow doctors to test for cancer and track treatment response.
New Study to Get More Minorities Involved in Genetic Testing
Dr. Nicolette Rodriguez leads the REGENERATE study to find the best ways to get more Black and Latinx Americans genetic testing for cancer.
Pancreatic Microbiome May Hold the Key To Better Treatment
Dr. Deirdre Cohen’s research into the pancreatic microbiome has found that gut bacteria may directly influence the effectiveness of immunotherapy.
A New Approach to MEK Inhibition for First-Line Treatment
Dr. Eileen O’Reilly outlines a phase III trial of a targeted therapy for patients with metastatic pancreatic cancer.
Pancreatic Cancer Pain Management a Zap Away
Dr. Yaacov Lawrence discusses the results of his clinical trial using SBRT radiotherapy for pain management of pancreatic tumors.
For Families at Risk, Remote Education May Be Key in Improving Genetic Testing Uptake
What’s the best way to educate families at risk for pancreatic cancer about genetic testing? Dr. Sapna Syngal discusses the results of the GENERATE study.
New Vaccine Harnesses Power Of the Lymph Nodes
A promising new vaccine targets KRAS, the most common mutation in pancreatic cancer. Dr. Shubham Pant provides an update.
Comprehensive Molecular Test Helps Classify Pancreatic Cysts
Dr. Aatur Singhi and colleagues are developing a test to help determine whether pancreatic cysts are likely to turn cancerous.