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Scientists Find Trigger that Sets off Metastasis in Pancreatic Cancer

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Pancreatic cancer, though rare, is one of the deadliest of cancers, killing nearly 50,000 people yearly and doing so quickly, primarily because it metastasizes rapidly through the body. Barely one in 10 people survive beyond five years. But a discovery by chemists at the University of California, Berkeley, suggests a new way to slow or stop metastatic spread of pancreatic and perhaps other cancers.

In last week’s issue of the journal Molecular Cell, Christopher Chang and his group at UC Berkeley, collaborating with Christine Chio’s team at Columbia University in New York, report that metastasis is triggered by the loss of an enzyme that repairs oxygen damage to proteins. Read more . . . 


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