In BRPC/LAPC patients (n= 155) treated at a high-volume institution with induction CTX followed by 5-fraction SBRT, the surgical, pathologic, and survival outcomes were analyzed.
Of 64 BRPC patients, 50 (78%) had resection; among those, R0 resection was achieved in 48 (96%) patients.
Of 91 LAPC patients, 57 (63%) had resection; R0 resection was achieved in 50 (88%) cases. Read more . . . .
Among patients with borderline resectable and locally advanced pancreatic adenocarcinoma (BRPC/LAPC) treated with induction multi-agent chemotherapy (CTX) followed by stereotactic body radiation therapy (SBRT), margin-negative (R0) resection was successfully achieved in a high proportion of patients but locoregional failure remained common, emphasizing the necessity to continue to optimize radiation delivery in this context.