Pancreatic ductal adenocarcinoma (PDAC) is the most common form of pancreatic cancer. The disease is almost always fatal, with a 10-year survival rate of around 1 percent. The prognosis is especially poor for a subgroup of these tumors known as mesenchymal PDAC subtype, where even the strongest combination chemotherapies do not improve the poor clinical outcomes. Read more . . .
Pancreatic carcinoma is a tumor with an extremely poor prognosis for which effective treatments have not yet been found. In a preclinical animal model with mice, a team of researchers has now discovered a way of making pancreatic tumors treatable with immunotherapy methods using a targeted combination of two cancer drugs. The researchers believe that the promising combined approach could also prove effective with other cancer types.