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One-Off Blast of RT Triggers Immune Response in Pancreatic Cancer

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A single dose of radiation to the tumor bed immediately after pancreatic surgery not only kills cancer cells but also creates an inflammatory microenvironment that triggers antitumor immune responses, according to early findings from researchers in South Korea.

The findings suggest that intraoperative radiotherapy (IORT) “may contribute to a positive feedback loop that continuously activates immune-related cells, thereby forming an immune environment that would improve local control of pancreatic cancer,” the team writes. The study was published online October 12 in BMC Cancer. Read more . . . 

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