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Surgery Plus Neoadjuvant Therapy Improves Survival in Margin-Positive Pancreatic Cancer

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Surgical resection demonstrated a notable survival benefit, particularly in combination with neoadjuvant therapy, in patients with aggressive margin-positive pancreatic cancer, according to data from an analysis published in the Journal of the American College of Surgeons.

Results from the analysis indicated that patients who received R1 and R2 surgical resection experienced a better overall survival (OS) vs those who received chemotherapy alone. Patients who underwent R1/R2 resection and neoadjuvant therapy experienced the best median OS of 19.75 months (95% CI, 17.91-22.28) vs 16.92 months with up-front surgery (95% CI, 16.03-17.81) and 9.04 months with chemotherapy alone (95% CI, 8.87-9.26). Read more . . . 

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