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Pancreatic Cancer Cells Hijack Muscle Protein to Beef Up Their Metabolism

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Cancer starts with mutations in a cell’s DNA, but new UC San Francisco research shows that the endurance of a tumor relies on its ability to rapidly evolve and adapt to challenges brought about by the environment in which it grows.

“A major obstacle cancer cells must overcome is their incessant need for more nutrients to fuel their accelerated growth,” said Rushika M. Perera, PhD, assistant professor of anatomy in the School of Medicine, who studies metabolic pathways in a cancer known as pancreatic ductal adenocarcinoma (PDA). PDA is an aggressive cancer that took the lives of Supreme Court Justice Ruth Bader Ginsburg and Congressman John Lewis, as well as 47,000 other Americans last year. Read more . . .

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