The team explained that pancreatic cancer is not alone in forming from the site of tissue damage, as many other cancers form the same way, for example, stomach cancer caused by Helicobacter pylori infection, Barrett’s oesophagus caused by acid reflux, as well as smoking-induced lung cancer. Read more . . .
According to researchers, tissue damage synergises with specific genetic changes to promote the onset of pancreatic cancer. In addition, the team found that over half of the epigenetic changes that typically characterise advanced pancreatic cancer were already present in these cells within 48 hours of tissue damage.