According to the scientists, pancreatic cancer has proven very difficult to treat with drugs. Not only do the tumours have a limited blood supply, making it hard to deliver drugs, they are also surrounded by stroma (a dense connective tissue) and tumour cells are protected by an extracellular matrix (a meshwork of proteins and carbohydrates). Read more . . . .
A pre-clinical study has used a highly selective, potent, engineered antibody-drug combination to induce marked and lasting tumour regression in a mouse model of pancreatic cancer. The study was conducted at Boston Children’s Hospital, US.