The pain is localized within the upper and middle abdomen by the visceral nociceptive signals traveling along sympathetic fibers to the celiac plexus nerves, which are located around the T12-L2 vertebrae. These signals are then carried to the splanchnic nerves at the T5-T12 dorsal root ganglia. Read more . . .
The treatment of abdominal pain related to pancreatic cancer can be very challenging. The origin of pain related to malignancy may be somatic, visceral, or neuropathic. Most of the pain is due to inflammation or tissue damage of the abdominal viscera and may include ductal obstruction.