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Mucins in pancreatic cancer: A Well‐Established but Promising Family for Diagnosis, Prognosis and Therapy

Mucins in pancreatic cancer: A Well‐Established but Promising Family for Diagnosis, Prognosis and Therapy
Mucins are a family of multifunctional glycoproteins that mostly line the surface of epithelial cells in the gastrointestinal tract and exert pivotal roles in gut lubrication and protection. Pancreatic cancer is a lethal disease with poor early diagnosis, limited therapeutic effects, and high numbers of cancer‐related deaths.

In this review, we introduce the expression profiles of mucins in the normal pancreas, pancreatic precursor neoplasia and pancreatic cancer. Mucins in the pancreas contribute to biological processes such as the protection, lubrication and moisturization of epithelial tissues.  Read more . . . .


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