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Integrated Epigenetic Biomarkers in Circulating Cell-Free DNA as a Robust Classifier for Pancreatic Cancer

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The high lethal rate of pancreatic cancer is partly due to a lack of efficient biomarkers for screening and early diagnosis.

We attempted to develop effective and noninvasive methods using 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) markers from circulating cell-free DNA (cfDNA) for the detection of pancreatic ductal adenocarcinoma (PDAC). Read more . . . 

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