YAP1 is an Independent Prognostic Marker in Pancreatic Cancer and Associated with Extracellular Matrix Remodeling

Pancreatic cancer is a major cause of cancer-related mortality. The identification of effective biomarkers is essential in order to improve management of the disease. Yes-associated protein 1 (YAP1) is a downstream effector of the Hippo pathway, a signal transduction system implicated in tissue repair and regeneration, as well as tumorigenesis.