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YAP1 is an Independent Prognostic Marker in Pancreatic Cancer and Associated with Extracellular Matrix Remodeling

YAP1 is an Independent Prognostic Marker in Pancreatic Cancer and Associated with Extracellular Matrix Remodeling
Pancreatic cancer is a major cause of cancer-related mortality. The identification of effective biomarkers is essential in order to improve management of the disease. Yes-associated protein 1 (YAP1) is a downstream effector of the Hippo pathway, a signal transduction system implicated in tissue repair and regeneration, as well as tumorigenesis.

Here we evaluate the biomarker potential of YAP1 in pancreatic cancer tissue. YAP1 was selected as a possible biomarker for pancreatic cancer from global protein sequencing of fresh frozen pancreatic cancer tissue samples and normal pancreas controls. Read more . . . 


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