They assessed peripheral leukocyte samples of 476 PDAC cases and 357 controls nested within the European Prospective Investigation into Cancer and Nutrition cohort for relative mtDNA copy number by a quantitative real-time PCR assay. They identified lower mtDNA copy number with advancing age and with a high BMI level. Read more . . .
Given the association of mitochondrial DNA (mtDNA) copy number in peripheral blood with risk of developing several cancers, researchers here sought for data on pancreatic ductal adenocarcinoma (PDAC).