The management of nonfunctional pNETs is controversial, according to the study. These tumors have a relatively low tendency to progress and removal is associated with potential morbidity. In some cases, patients with these smaller tumors are put under observation, while other experts advocate for removal because of malignant differentiation, lymph node metastases, or distant metastasis. Read more . . .
Data from a new study of a large US multi-institutional cohort of patients with pancreatic neuroendocrine tumors (pNETs) suggested that resection with lymphadenectomy should be considered in those with nonfunctional tumors 1.5 cm to 2 cm in size.