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Gene Mutation, Tissue Location, Signaling Networks Drive Cancer Incidence and Severity

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The KRAS gene is one of the commonly mutated genes in cancer. 

More than 40 percent of colorectal cancers have a mutated KRAS gene, or oncogene, that is at least partially responsible for cancer development. Mutated KRAS genes are commonly found in other cancers as well, including pancreatic, lung, myeloma and endometrial, and not all KRAS mutations in the same organ tissue cause the same disease severity, according to three new studies from researchers at the Cancer Center at Beth Israel Deaconess Medical Center (BIDMC). Read more . . . 

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