Cancer is relentless and resilient. When a drug blocks a cancer cell’s main survival pathway, the cell avoids the obstacle by taking different pathways or detours to save itself. This tactic is called “developing resistance,” and it’s one of the key challenges researchers face when seeking effective therapeutics to combat pancreatic ductal adenocarcinoma (PDA).
A group of researchers at Cold Spring Harbor Laboratory (CSHL) has now found a way to tackle this problem and stop the growth of pancreatic tumors in mice. Their findings are published in the journal Clinical Cancer Research. Read more . . .