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A Phenome-Wide Mendelian Randomization Study of Pancreatic Cancer Using Summary Genetic Data

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The 5-year mortality rate for pancreatic cancer is amongst the highest of all cancers. Greater understanding of underlying causes could inform population-wide intervention strategies for prevention.

Summary genetic data from genome-wide association studies (GWAS) have become available for thousands of phenotypes. These data can be exploited in Mendelian randomization (MR) phenome-wide association studies (PheWAS) to efficiently screen the phenome for potential determinants of disease risk. Read more . . .

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