The success of chimeric antigen receptor (CAR) T-cell therapy observed in hematologic malignancies has not yet translated into the solid tumor setting; however, efforts continue to try to bring this new modality into the treatment paradigm for solid tumors, including pancreatic cancer.
Barriers to efficacy of CAR T cells in this setting were discussed by Gregory L. Beatty, MD, PhD, at the 2019 American Society of Clinical Oncology-Society for Immunotherapy of Cancer Clinical Immuno-Oncology Symposium. Read more . . .