Researchers at the Johns Hopkins Kimmel Cancer Center discovered a combination of a cancer vaccine with two checkpoint drugs reduced pancreatic cancer tumors in mice, demonstrating a possible pathway for treatment of people with pancreatic cancers whose response to standard immunotherapy is poor.
Results of the experiments combining an immune system booster vaccine called PancVAX with two checkpoint drugs derived from anti-PD-1 and agonist OX40 antibodies were published in the journal JCI Insight in October 2018. Read more . . .