A Peptide-CpG-DNA-Liposome Complex Vaccine Targeting TM4SF5 Suppresses Growth of Pancreatic Cancer in a Mouse Allograft Model

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Recently, clinical trials based on therapeutic strategies targeting specific proteins and/or pathways have shown significant advances in many tumor types. However, in pancreatic cancer, these trials were proven not successful.

The purpose of this study was to evaluate possible utility of TM4SF5 to treat pancreatic cancer using a mouse allograft model. Read more . . .