Researchers Identify Resistance Mechanism to Possible Pancreatic Cancer Treatment

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Despite decades of research, treatments that can target a common mutation in the most frequently diagnosed type of pancreatic cancer have remained elusive. Now, University of North Carolina Lineberger Comprehensive Cancer Center researchers report they have discovered a mechanism of resistance to a treatment they’d identified as promising.

In the journal Cancer Cell, UNC Lineberger’s Channing Der, PhD, and his colleagues describe how pancreatic cancer may develop resistance to ERK inhibitors in pancreatic cancer. Yet, researchers believe they have identified a potential therapeutic solution to the problem that they hope will spur pharmaceutical research and development. Read more . . .