Association Between Inherited Germline Mutations in Cancer Predisposition Genes and Risk of Pancreatic Cancer
Are there germline mutations in cancer predisposition that are associated with pancreatic cancer?
In a case-control study that included 3030 patients with pancreatic cancer and 123 136 reference controls, 6 genes were independently associated with pancreatic cancer, with odds ratios between 2.58 and 12.33 after correction for multiple comparisons. In aggregate, these genes were observed in 5.5% of patients with pancreatic cancer. Read more . . .
