Obesity inhibits key cancer defense mechanism

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Obesity is a known risk factor for certain types of cancer, including colon, pancreatic and breast cancer. Studies have shown its role in promoting tumor growth and malignant progression. But its role in cancer initiation has been uncertain.

“Epithelial” cells lining the surfaces of organs have the intrinsic ability to remove potentially malignant cells from their midst. This is called the “epithelial defense against cancer” mechanism. Normally, the cells sense harmful cells and push them out by the process called cell competition. Read more . . .