To starve pancreatic tumors, researchers seek to block ‘self-eating,’ other fuel sources

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To get the extra energy they need to fuel their uncontrolled growth, cancer cells break down some of their own parts for fuel – a process known as autophagy, or “self-eating.”

Researchers from the University of North Carolina Lineberger Comprehensive Cancer Center found a possible therapeutic strategy to block self-eating in one of the deadliest cancers, as well as to cut off the tumor’s other energy sources.

The researchers are reporting preclinical findings for a potential two-treatment strategy to block multiple mechanisms of cancer cell metabolism in pancreatic cancer at the American Association for Cancer Research Annual Meeting in Chicago. Read more . . .


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