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Modifying Oncolytic Adenoviruses to Target Pancreatic Cancer

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The cancer we are working on is called pancreatic ductal adenocarcinoma (PDAC), a very aggressive cancer of the pancreas.

Luckily, it is not a very common cancer, but there are hundreds of thousands of cases a year in the U.K. and the U.S., but it is not as common as prostate, lung and breast cancer. Sadly, it has the highest mortality rate of all cancers, with a five-year survival rate of less than 5%, and that hasn’t changed for the last 40 years.

One of the reasons for this is that pancreatic cancer is often discovered late. This is due to a lack of characteristic symptoms, which are easily missed by the general practitioner. These include diffused stomach pain and diffused back pain, which can have many other causes. Read more . . . 

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