A Gene that Increases the Risk of Pancreatic Cancer Controls Inflammation in Normal Tissue

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Inflammation is a defensive response of the body to aggression, but when it persists it can be harmful and can even predispose the subject to cancer. Hence, it is crucial to understand fully the relationship between inflammation and cancer.

A group of researchers at the Spanish National Cancer Research Centre (CNIO) has now discovered an unexpected link between the two processes: in the pancreas, one of the genes that increases the risk of developing pancreatic cancer also controls inflammation. This finding offers “a major conceptual change”, explains Paco Real, from the CNIO, which, as well as helping to understand the origin of tumours, suggests new strategies to improve the prevention of pancreatic cancer. Read more . . .