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New Assay May Help Predict Which Pancreatic Lesions May Become Cancerous

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A report in The Journal of Molecular Diagnostics, describes a new simple molecular test to detect chromosomal abnormalities—biomarkers known as telomere fusions—in pancreatic tumor specimens and pancreatic cyst fluids.

This assay may help predict the presence of high-grade or invasive pancreatic cancers requiring surgical intervention.

More sophisticated imaging of the pancreas has led to increased detection of presymptomatic lesions. The detection of telomere fusions has the potential to help physicians determine whether these lesions have a high likelihood of developing into pancreatic cancer requiring surgical resection or are more likely to be benign and can be followed by “watchful waiting.” Read more . . .

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