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Study Identifies Protein as Potential Therapeutic Target for Pancreatic Cancer

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A protein known as arginine methyltransferase 1 (PRMT1) may be a potential therapeutic target for pancreatic ductal adenocarcinoma (PDAC), the most common type of pancreatic cancer, and one of the most deadliest with a less than 10 percent, five-year survival rate.

PRMT1 is involved in a number of genetic processes including gene transcription, DNA repair and signaling.

“Our study has identified and validated for the first time an arginine methyltransferase as a novel genetic vulnerability in PDAC,” said Giulio Draetta, M.D., Ph.D., professor of Genomic Medicine and director of Institute for Applied Cancer Science (IACS) at The University of Texas MD Anderson Cancer Center.  Read more . . .

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