Without interference from gamma delta T-cells, tumor-attacking T-cells like CD4 and CD8 should be able proliferate and go after pancreatic cancer cells, which they now do not.
The study, “γδ T Cells Support Pancreatic Oncogenesis by Restraining αβ T Cell Activation,” recently published in Cell, was developed by researchers at the New York University (NYU) School of Medicine, and suggests that targeting gamma delta T-cells in pancreatic cancers may improve the work of immunotherapies in boosting tumor-fighting T-cells. Read more . . .