The article focuses on how experts from different fields are pooling their knowledge to form teams to tackle tough-to-treat diseases such as pancreatic cancer. The effort is funded by Stand Up To Cancer.
“Structurally, pancreatic cancer is like an oatmeal-raisin cookie, says David Tuveson, deputy director of the Cold Spring Harbor Laboratory’s Cancer Center, whose lab is also focused on the disease. The raisins represent tumor cells. The oatmeal surrounding the raisins is the stroma. The challenge for researchers, he says, is “to get the treatment through the oatmeal to the raisins.”
That has proved a frustrating task. Over the past few decades, multiple strategies to penetrate or strip away the stroma and deliver a killer dose of medicine to the tumor have failed. “The way this cancer develops, it’s a very tough nut to crack,” says Ronald Evans, director of the Gene Expression Laboratory at the Salk Institute, La Jolla, Calif., and co-leader of a separate team studying pancreatic cancer with funding from Stand Up To Cancer.”
To learn more about what Tuveson and Evans are working on, and how collaboration is taking aim at pancreatic cancer, read the full article in the Wall Street Journal.