Voruciclib Regimens Demonstrate Preliminary Potency Against KRAS-Positive Cancers
Treatment with voruciclib, a CDK9 inhibitor, as a monotherapy or in combination with sotorasib (AMG 510) and adagrasib demonstrated early…
Immune-Stimulating Drug Before Surgery Shows Promise in Early-Stage Pancreatic Cancer
The data--which included 16 patients treated with the CD40 agonist selicrelumab--was presented today by Katelyn T. Byrne, PhD, an instructor of…
Clear Need for Sensitive Diagnostic Markers for Pancreatic Cancer Surveillance
“Nevertheless, timely identification of resectable lesions proved challenging despite the concurrent use of two imaging modalities, with [endoscopic ultrasonography (EUS)]…
Pancreatic Cancer Cells Hijack Muscle Protein to Beef Up Their Metabolism
“A major obstacle cancer cells must overcome is their incessant need for more nutrients to fuel their accelerated growth,” said Rushika…
Municipality and Adjusted Gross Income Influence Outcome of Patients Diagnosed with Pancreatic Cancer in a Newly Developed Cancer Center in Mercer County New Jersey, USA, a Single Center Study
Our hypothesis was that specific variables such as socio-economic status or race could be linked to the outcome of patients…
Ongoing Research Is Slated to Optimize Sequencing With Current Standards in Pancreatic Cancer
In the frontline setting, FOLFIRINOX or gemcitabine plus nab-paclitaxel (Abraxane) remain standard of care options for patients with metastatic pancreatic…
Methylation Patterns Partition PCancer into Distinct Prognostic Subtypes
The 298 OS-related methylation sites in the training cohort were selected for consensus clustering, and the authors identified three subtypes…
SNUH Researchers find Genetic Variation for Pancreatic Cancer
Pancreatic cancer has a low five-year survival rate of about 10 percent as 80 to 85 percent of the patients…
Upregulated MicroRNA-483-3p is an Early Event in Pancreatic Ductal Adenocarcinoma (PDAC) and as a Powerful Liquid Biopsy Biomarker in PDAC
miR-483-3p is overexpressed in the tumor tissue of pancreatic duct adenocarcinoma, but its potential as noninvasive biomarker remains unknown. Read…
Definitive Ablative Radiation Therapy in Inoperable Locally Advanced Pancreatic Cancer
As stated by the investigators, “Surgical resection has been considered the only curative option for patients with pancreatic cancer. Nonoperative…