Immunotherapy to Attack a Common Pancreatic Cancer Mutation
Researchers are testing a type of immunotherapy to attack a variant of the KRAS mutation; KRAS mutations occur in almost all pancreatic cancers.
Testing a New Drug to Attack Pancreatic Tumor Blood Vessels
A clinical trial is testing a new drug combination that damages the tumor blood vessels and allows chemotherapy drugs to enter the tumor.
A New Drug to Target Cancer Cell Enzymes
This trial remains active but is no longer recruiting participants. In patients with metastatic pancreatic cancer, researchers are comparing FOLFIRINOX, the standard treatment, with FOLFIRINOX plus CPI-613, a new drug that works on enzymes involved in cancer cell energy metabolism. Target: Enzymes Mitochondria are components within a cell that are responsible for generating the energy…
Immunotherapy for Advanced Pancreatic Cancer and Other Solid Tumors
Researchers are testing the use of tumor-infiltrating lymphocytes, a type of immunotherapy, against advanced pancreatic cancer.
Immunotherapy to Enhance Standard Chemotherapy for Advanced Pancreatic Cancer
Researchers are testing an immunotherapy drug approved for other advanced cancers for effectiveness against pancreatic cancer.
Targeting Cancer-Associated Wasting With Experimental Immunotherapy
Wasting, or cachexia, is the focus of a clinical trial testing a cachexia immunotherapy treatment combined with standard pancreatic cancer treatment.
Testing a Different Approach to Pancreatic Cancer Treatment
This trial remains active but is not recruiting at this time. A pancreatectomy or Whipple procedure can remove a patient’s main tumor, but post-surgical testing of lymph nodes and the edges of the tissue left after surgery often finds cancer cells. These patients are at high risk of recurrence of the disease. Researchers are trying…
Combining Immunotherapy and Targeted Therapy for Pancreatic Cancer
Researchers are combining immunotherapy and targeted therapy in a clinical trial for pancreatic cancer patients on platinum-based chemotherapy.
Electric Fields to Enhance Pancreatic Cancer Chemotherapy
A clinical trial uses electric fields to help slow the growth of tumor cells, In a clinical trial for pancreatic cancer patients.
Immunotherapy Combination Plus Radiation for Pancreatic Cancer
Researchers are testing two monoclonal antibodies approved to treat melanoma plus radiation as a treatment for pancreatic cancer.