skip to Main Content
Newsfeed image, light gray text on dark gray background

Gut Bacteria Linked to Immune Suppression in Pancreatic Cancer: Study

Lactobacillus – a type of bacteria thought to promote gut health – can alter the function of immune cells called macrophages in the pancreatic tumour environment and spur cancer growth, the researchers found. “Most studies focus on positive correlations between the microbiome and cancer outcomes,” said Tracy McGaha, a senior scientist at Princess Margaret Cancer Centre,…

Newsfeed image, light gray text on dark gray background

That New Fitbit Does More Than Count steps. It May Save Your Life One Day

Working with surgeons from the School of Medicine, Lu’s team has turned a Fitbit into a life-saving element of clinical care. Take pancreatic cancer. One of the best treatment options is surgery, Lu said, but it’s extremely risky. “Do you go through with the surgery or not? It’s a tough decision. But if you can predict…

Newsfeed image, light gray text on dark gray background

​New Findings on Bacteria that Increase Risk of Pancreatic Cancer

Cystic lesions, including intraductal papillary mucinous neoplasms (IPMNs), of the pancreas are common. Because they are known as precursors to pancreatic cancer, many patients need regular, lifelong check-ups, and a few can also require surgery. It would be valuable for the individual and for the health care to know more about the carcinogenic risk factors.…

Newsfeed image, light gray text on dark gray background

Pant Projects an Expanding Role for Targeted Therapy in Pancreatic Cancer

In today’s episode, we had the pleasure of speaking with Shubham Pant, MD, an associate professor in the departments of Investigational Cancer Therapeutics and Gastrointestinal Medical Oncology, and associate director in the Department of Sheihk Ahmed Center for Early Phase Drug Development of Pancreatic Cancer Research, in the Division of Cancer Medicine, at The University…

Newsfeed image, light gray text on dark gray background

Voruciclib Regimens Demonstrate Preliminary Potency Against KRAS-Positive Cancers

Treatment with voruciclib, a CDK9 inhibitor, as a monotherapy or in combination with sotorasib (AMG 510) and adagrasib demonstrated early activity in KRAS-mutant cancer cell lines, and synergistically inhibited growth of KRAS-mutant cancers in preclinical models, according to findings presented during Week 1 of the 2021 AACR Virtual Annual Meeting. Read more . . .

Newsfeed image, light gray text on dark gray background

Alterations of Asymmetric Dimethylarginine (ADMA)-Containing Protein Profiles Associated with Chronic Pancreatitis Pathogenesis

Totally 36 patients with CP were enrolled in this study. Seven other cholangiocarcinoma patients without pancreas involvements or patients with benign pancreatic tumors were included as the control group. Total proteins in human pancreatic tissues were digested by trypsin, and ADMA-containing peptides were enriched via immunoaffinity purification. The LC-MS/MS was performed to characterize ADMA-containing peptides…

Newsfeed image, light gray text on dark gray background

Clinical Study Simplifies Precision Medicine for Pancreatic Cancer Patients

With more than 10 years of clinical and genomic data from the COMPASS trial, OICR-supported researchers have recently discovered a new, simplified way to match patients with the most appropriate treatment for their disease by measuring the expression of two genes, GATA6 and Keratin 5. Their discovery was recently published in Clinical Cancer Research. Read more…

Newsfeed image, light gray text on dark gray background

Screening for pancreatic cancer using artificial intelligence

Due to such a low incidence of this disease, screening the whole population is neither practical nor appropriate. Current diagnostic markers are very expensive per cancer and are challenged by cost and morbidity associated with invasive testing. Read more . . . 

Back To Top