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All stories …

My Treatment, Managing Pancreatic Cancer, Promising Science, and Clinical Trials stories provide information to fight pancreatic cancer.

Keeping the battle going
A conversation with a physician-scientist
Believing in myself and my doctor
Moderating a hormone to make a standard chemotherapy more effective
Retrospective study compares FOLFIRINOX with gemcitabine plus nab-paclitaxel
Testing leads to clinical trial
Potential to signal multiple cancers and their locations
Making choices for pancreatic cancer treatment
Testing ways to make standard treatment more effective
NAPOLI-3 phase III trial underway
Choosing quality of life
Aims to prove GATA6 can provide important information in neoadjuvant settings
A rapid response helps everything fall into place
Trying a drug approved for another disease
Now open to those with a first-degree relative with pancreatic cancer
Taking on PNET with all I have
A different kind of ablation for stage III pancreatic cancer
Making choices for my survival
Using irreversible electroporation to make chemotherapy more effective
Research focused on HuR and IDH1 provides new insights
Coaching the coach through a serious illness
COMBAT trial using triple therapies shows promising results
Chicken Enchiladas and Pancreatic Cancer
Combining a new drug with standard treatment
PRECEDE Consortium and Project Purple join forces
Family history of the disease leads me to early detection trial
Exploiting vitamin C’s ability to disrupt cancer metabolism
Different doctors at different locations make an effective treatment plan
Combining an engineered antibody and an anticancer agent to specifically kill tumor cells
Second-round Challenge Grant funding to develop personalized vaccines
BRCA2 mutation and a family history of cancer
Treatments targeted to tumor molecular profile increase survival
First steps in pancreatic cancer treatment
Finding another way to slow or stop the spread of the cancer
Four teams awarded second-round funding
Lessons for finding good treatment options
Tumor treating fields may prove beneficial in locally advanced pancreatic cancer
Two bouts of pancreatic cancer but still optimistic
Adding two types of immunotherapy to chemotherapy
Dana-Farber team researching ways to make targeted therapy more effective
Making quilts to comfort patients and raise money for research
Targeting RNA, the work order of a cell
Researching, reading, and making choices after genetic testing
Using a washing solution to check the spread of cancer cells
Why master regulators matter
Helping others through
Understanding the clinical trials process
Recovering from stage IV pancreatic cancer
Trying a combination across cancers
Getting the most from radiation treatment
Continue with maintenance chemotherapy or take a break?
Small progress lays groundwork for the future
Grateful for a second opinion
Looking for a better presurgical treatment
Discovering a new contributor to disease development
Facing ongoing treatment for PNET
A new study may bring pain relief to more
Rare gene fusion found
Combining a new type of radiation treatment with chemotherapy
Autopsy samples provide more information about the disease
Moving quickly into treatment after a pancreatic cancer diagnosis
The importance of learning about familial mutations
Working with research centers for the latest treatments
Trying to find a method for diagnosing pancreatic cancer at an earlier stage
Stopping a communication breakdown in cells
Petitioning my HMO for the doctors with more experience
Targeting pancreatic cancer metastases
Making a treatment plan and then quickly changing it
Getting directly to the tumor may make a difference
CompCyst can help identify potential cancers
Fantasy sports are a helpful distraction during treatment
Immunotherapy trial with a promising target
Facing treatment three times
Comparing two treatment protocols
Mutations make a difference in treatment options
Not giving in to stage IV pancreatic cancer
Status changes in diabetes patients can indicate cancer
Great response to chemotherapy makes surgery possible
Trying to improve treatment for patients who cannot have surgery
Trying combinations to make immunotherapy work for pancreatic cancer
Giving back to the pancreatic cancer community after treatment
The latest research suggests depression may be an early warning sign of pancreatic cancer
Looking for a treatment plan
Working against the KRAS mutation
Cooperation and collaboration to benefit patients
Calling on my coaching skills to get through treatment
Learning more about inherited mutations
Learning to stay positive with a difficult disease
A combination to better slow or stop tumor growth
New treatment options for some patients
The value of genetic testing— finding a BRCA mutation
Seeking a way to reduce treatment-related hospitalizations
A clinical trial instead of standard treatment alone
Adding a new drug to standard treatment
Chemotherapy responses vary among populations
Researching and traveling for treatments
A possible predictor for longer survival
A surprising find in surgery
A combination of therapies to stimulate the immune system
Understanding the relationship between metabolism and survival
Educating myself to make the best treatment choices
Two targets get for a better result for patients
Beating one challenge leads to taking on another
Trying an immunotherapy drug that works on similar tumor types
BRCA1/2 mutations point the way to a potential treatment
A blocked bile duct leads to diagnosis
Finding another route to effective treatments
Long road of testing finally leads to a diagnosis
Combatting a condition affecting patients with advanced pancreatic cancer
Precision radiation for pancreatic tumors
Odd pain leads to pancreatic neuroendocrine tumor diagnosis
Bacteria in the pancreas may impact immunotherapy
Qualifying for an immunotherapy drug
A drug for bone marrow and blood diseases that may help pancreatic cancer
A new study results in recommendation changes
Quality of life includes increasing my time with my family
Targeted therapy now available
Genetic testing changed my treatment plan
Comparing combinations to battle advanced pancreatic cancer
Treatment gains and next steps
The right treatment made me believe I could survive
A rare (at the time) operation leads to long-term survival
Two clinical trials take on the immune system
Combining two different approaches to slow tumor growth
Participating in trials helps everyone
Focusing on a receptor associated with chemotherapy resistance
A family history leads me to push for a diagnosis
Assessing risks and treatment options for patients and families
A former basketball coach shares his thoughts
Trying treatments that are effective on other cancers
New study aims to fill treatment gap
Traveling to Boston gets me into a research study
A comparison of possible early detection methods
Targeting a tumor marker
Treatment leads to long-term survival
Majority of states and patients approve
A serious medical crisis uncovered an even more serious cause
Producing an immune response to a patient’s tumor
A step-by-step plan to combat my pancreatic cancer
A new version may improve on an older drug
Innovative treatment makes all the difference
Using targeted radiation during chemotherapy
Why immunotherapy has had limited success against pancreatic cancer
A vow to fight hard for my young family
Another approach to finding pancreatic cancer earlier
Learning about the disease to make educated treatment choices
A different type of immunotherapy
Finding ways for pancreatic cancer patients to live longer
Not even Hurricane Harvey can stop my battle
Adding vitamin D to a drug combination
A different treatment plan for some patients
Resection or NanoKnife as the goal
Exploring a treatment targeted to carriers of certain mutations
Taking the reins to get into a clinical trial
Increasing the possibility of finding pancreatic cancer at its earliest stages
Chemotherapy, a common high blood pressure medication, immunotherapy, and radiation under study
A unique treatment plan works for me
Adding to a combination that includes an antimalarial drug
An active life with pancreatic cancer
Making radiation possible at higher doses
These “mini-tumors” may help personalize pancreatic cancer treatment
An opportunity for a clinical trial from a bad diagnosis
A possible reason why cancer spreads after surgery removes a tumor
Vague symptoms add up to pancreatic cancer
A new drug for pancreatic cancer patients who qualify for surgery
Two types of immunotherapy team up to tackle pancreatic cancer
My doctor followed up on vague symptoms
Changing the outer layer of cancer cells
Focusing on those who defied the odds in all fields
A possible new way to stop PNETs
Learning more about familial pancreatic cancer
A mutation means close monitoring for other cancers
Weight loss alerts family doctor at annual physical
Increasing the possibility of surgery to increase the possibility of survival
New treatments plus an experienced surgical team change the picture
A chemotherapy regimen designed for me
Molecular profiling can direct early stages of treatment
Breaking through the fibrous layer to possibly make the cancer removable
My doctor wanted to look further because of my history of gastrointestinal problems
A noninvasive method for catching cancer earlier
Seeking a more effective treatment for pancreatic neuroendocrine tumors
Triathlon training helps me feel like myself despite having pancreatic cancer
Research into understanding the relationship between stroma and tumors
A treatment to decrease the likelihood of remaining cancer cells in tissue margins after tumor removal surgery
Intuition leads to early diagnosis
Boosting the odds for successful immunotherapy
A combination to arrest the spread of pancreatic cancer
A doctor with a more positive attitude helps me through treatment
Making stenting more effective at unblocking bile ducts
Sharing my cancer journey as I travel brings the support of many
Comparing two regimens that combine different treatments
Choosing the treatment to make my life the most comfortable
Explaining the different mutations
Attacking the proteins that encourage cancer growth
Surgery for benign IPMN tumor leads to monitoring for pancreatic cancer
Learning to reprogram the pancreatic tumor microenvironment
A trial for advanced pancreatic and colorectal cancers
Learning to take charge of my treatment
The benefits of participating in a clinical trial
A new class of drug to work with existing treatment
Looking for a clinical trial
A look at the status of immunotherapy
A multi-pronged approach to making tumors removable
I was screened annually because of a family history of pancreatic cancer
More genetic information can help bring about early detection tests
Pairing drugs for two different types of cancer
Traveling to get the treatment I needed
An old school risk assessment tool makes a comeback
A multipronged attack to stop a pancreatic tumor
Trying different treatments to battle recurrent cancer
A way to help doctors identify early detection and screening options
Making platinum compounds work better
Chemotherapy, radiation, and surgery have given me more time
Ongoing phase III trial hopes to confirm early findings
Testing an additional drug for increased response
Staying informed about treatment options helps me battle recurrences
Simple blood test can pick up disease at various stages
Studying the safety of an immunotherapy and vitamin D combination
My quality of life is very important
A clinical trial for my future and future patients
Screening and early diagnosis remain beneficial
A new drug may work where previous chemotherapy has not
A Whipple and a clinical trial gave my husband a chance at survival
A much-needed option for some pancreatic cancer patients with advanced disease
Adding an experimental drug to standard treatment
Good health is allowing me to support others
Comparing drugs and growing organoids
Testing a PARP inhibitor as an alternative to platinum-based chemotherapy
Blocking the molecules necessary for pancreatic cancer growth
A shocking diagnosis leads quickly to treatment
Stopping cancer cells from regrowing
BRCA-like genetic mutation determines treatments
Ongoing clinical trials investigating treatment with targeted high-dose radiation
Using tumor genetics to determine treatment
My third act as a pancreatic cancer activist
Although the jury is still out, more research is showing a potential link.
A diagnosis, then a treatment plan
A growing number of oncologists are extending survival rates using low-dose combination chemotherapy
Trying a PARP inhibitor, which is known to be more effective in BRCA carriers
Testing positive for the BRCA-2 mutation leads to a different treatment
Changing hospitals leads to a change in treatment
A new type of clinical trial
A new clinical trial to test what was found in the lab
I took a chance as the first patient on this trial
A two-phase trial compares the effectiveness of different drugs and radiation in cancer that has been surgically removed
Vitamin may make it easier for chemotherapy to reach the tumor
My treatment was tailored for me
Treatment before and after surgery to prevent the disease from spreading
Chemotherapy and specialized radiation treatments stop my tumor from growing
Testing other uses for drugs that appear to have cancer-fighting properties
Choosing a different type of treatment
Testing to see if this approach will make standard treatment more effective
Presurgical chemotherapy and new surgical techniques are being tested
Finding the drugs that will work best on my tumor
A possible route to surgery for locally advanced cancer
Finding this disease before it spreads will save lives
Even though it was cut short, it was successful
A trial for NanoKnife surgery
Innovative Clinical Trial Design Hopes to Improve Pancreatic Cancer Survival
A change in staging changes the treatment plan
A clinical trial for pancreatic cancer patients whose previous treatment has stopped working
My young child and my fiancé help motivate me for surgery
Changing signaling at the cellular level to fight cancer
A five-year program to accelerate efforts to prevent, diagnose, and treat cancer
Potentially curative surgery was the goal
Making chemotherapy work for people with particularly resistant cancer
Urine or blood-based test finds gene mutations
Personalized chemotherapy makes life more comfortable
Looking at the safety of a new drug
Making the case for clinical trials as standard of care
All treatments include clinical trials
Slowing the progress of locally advanced cancer
Clinical trials are looking at many different approaches
Because of my mother’s experience I knew what to do
A new combination to make pancreatic cancer more treatable
Early-stage clinical trials show patients with BRCA mutations may respond to therapies targeting DNA repair
Making a dire diagnosis livable
Exploring the value of vitamin C as part of cancer treatment
Standard of care treatment to prevent tumors from spreading
Making this cancer findable at an earlier stage
A focus on patients with a history of breast or ovarian cancer
A new drug, advanced radiology technique, and standard chemotherapy
Going to the right hospital is important
Applying evolutionary biology to solve cancer
Radiotherapy to treat cancer that may be left after surgery
The goal was surgery to remove the tumor
Targeting tumor pressure may hold key to more effective treatment
Looking for an effective short-term treatment to halt the disease
Keeping a positive attitude
A different combination of chemotherapies and radiation
The location of the tumor changed the initial plan
Basic research focuses on finding effective treatments for weight and muscle loss
A trial for pancreatic cancer patients who carry breast cancer gene mutations
A heritage of breast and ovarian cancer leads to vigilance about my health
Blocking a tumor’s blood supply to stop its growth or spread
Using highly targeted radiation for stage III pancreatic cancer
A strategy based on mimicking the suppression of antioxidant-promoting NRF2
Preventing metastasized cancer from progressing
Combining clinical experience with scientific endeavors
Getting treatment at a place that treats YOUR cancer
Finding another use for a drug typically given for other diseases
National familial pancreas tumor registry hopes to find answers
Combination of chemotherapy and radiation shrink the tumor for surgical removal
Trial also looks for genes associated with relapses
New-onset diabetes in patients over 50 can be a harbinger of disease and a new study seeks to find out why
My diagnosis of pancreatic cancer changed the direction of my retirement
Comparing a standard chemotherapy with treatment that uses two forms of immunotherapy
Tiny tumors grown in culture may help doctors personalize patient treatment
When one trial stops working, look for another trial
Recruiting patients for an immunotherapy trial
Allowing patients to live comfortably during treatment
The research falls under the umbrella-term “pharmacogenomics.”
What if a patient tests positive for a mutation associated with several types of cancer?
Genetic counseling and platinum-based chemotherapy
Researchers are discovering new ways to harness that power against pancreatic cancer.
A new standard of care for second-line treatment
Many patients aren’t armed with all the questions they ought to ask.
Vitamin C, in high enough doses, can stop those KRAS-mutant cancer cells in their tracks.
My family and I decided to get another opinion
In most cancers p53 has mutated and lost its ability to function
She never knew that she had saved at least one person
Researchers are now trying combinations of immune-based therapies
Knowledge of my BRCA2 status directed treatment choices
A family history of pancreatic cancer leads to annual screening
Each person’s story is different, everyone’s treatment is unique
My stage IV pancreatic adenocarcinoma diagnosis led me to clinical trials
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