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All stories …

My Treatment, Managing Pancreatic Cancer, Promising Science, and Clinical Trials stories provide information to fight pancreatic cancer.

Getting chemotherapy to the tumor more efficiently
Comparing PARP inhibitor to monitoring-only approach after surgery and chemotherapy
Facing down PNET
Looking back at this past year’s advances
Educating others so they can be helped sooner
A platform trial to test personalized treatment
A new immunotherapy approach
Awareness of subtle symptoms saved my life
Trials are part of Lustgarten’s Clinical Accelerator Initiative
Treatment at a major academic center or cancer hospital
Matching treatment to tumor subtype
Virtual conference showcases progress in pancreatic cancer research
Reflecting on my treatment journey
Lustgarten program keeps trials small to generate results more quickly
Getting a second opinion
Developing an immune response to the tumor
New combination shrinks or eliminates tumors in preclinical study
Learning a new meaning for “treatment”
Tumor microbiome may hold clues to more effective treatments
My goal was to be cancer-free
More scientific research on the tumor microenvironment and metabolism
Day One shows depth and breadth of pancreatic cancer research
Family history of pancreatic cancer leads to a clinical trial
High-dose vitamin C may prove beneficial in lung, colon, and pancreatic cancers
PNET leads me to start writing romance novels
A possible treatment if earlier chemotherapy has not worked
Finding ways to target KRAS mutations
More than prediabetes
Devimistat shuts down metabolic pathway to increase cell sensitivity to chemotherapy
Combining an old medicine and a new medicine
Targeting mutations to treat advanced pancreatic cancer
Racial and ethnic minorities are underrepresented despite incidence rates
Updating the stories of some people on clinical trials
Research may lead to better tools to predict treatment choice and outcomes
Finding the best treatment for me
Screening at-risk people
Both initial cancer and a recurrence caught early
A pound of prevention for pancreatic cancer progression
PanCAN’s Early Detection Initiative aims to find out
Traveling to see someone recommended
Leveraging a new technology to develop a better treatment for pancreatic cancer
Learning more about the diabetes–pancreatic cancer link
Treatment and prayer
Targeting the VEGF receptor in combination with mFOLFIRINOX not as effective as hoped
Mutation makes certain treatments more likely to be effective
Keeping surgically-removed pancreatic cancer at bay
New drug aims to starve and kill cancer cells
Listening to my gut
Urine may prove to be the most patient-friendly approach to the liquid biopsy
On the road after pancreatic cancer treatment
Combining treatments for advanced disease
Researcher aims to harness power of technology
A global pandemic can’t stop ongoing research
Looking for the right surgeon
An update on the phase II trial
Flexible neoadjuvant treatment plans
Biomarker-driven strategies for treatment
A long road to recovery
Teaching the body to attack a common mutation
Getting treatment and staying safe
Looking for a way to make standard treatment more effective
New assay analyzes circulating tumor cells and invasive cells
I still have time to smell the roses
OncoTreat platform tests feasibility of personalized medicine
Putting up my dukes and fighting this disease
#TumorBoardTuesday focuses on molecular alterations
Moving forward from the lab to clinical trials
Lifestyle risk factors play a possible role in pancreatic cancer diagnosis
New study focuses on rare NRG1 fusions
A post-treatment scan catches a bigger threat
Which regimen works best
Unprecedented challenges to the science community
The role of positive thoughts in my pancreatic neuroendocrine cancer treatment
Scientists are closer to understanding the biology of the devastating wasting syndrome
Exercise, Diet, and Treatments
Changing a nutrient to help patients
A broad range of experts helps develop strategies for early detection
Genetic testing showed the best treatment for me
Changing my doctor led to a better treatment for me
Study aims to make clinical trial process faster, more effective, and more cost-efficient
Investigational drug for pancreatic and other cancers
Managing treatment during the COVID-19 pandemic
Ongoing research about RNA subtypes may change treatment paradigms
Being proactive leads to early diagnosis
Combining a new agent with other already approved drugs
Talking with one of the world’s top cancer researchers
Pancreatitis leads to vigilance about my pancreas
Precision medicine and metabolism take center stage
Focus on tumor microenvironment and metastasis
Many coincidences lead to early diagnosis
Testing to find the best dose
Keeping the battle going
A conversation with a physician-scientist
Believing in myself and my doctor
Moderating a hormone to make a standard chemotherapy more effective
Retrospective study compares FOLFIRINOX with gemcitabine plus nab-paclitaxel
Testing leads to clinical trial
Potential to signal multiple cancers and their locations
Making choices for pancreatic cancer treatment
Testing ways to make standard treatment more effective
NAPOLI-3 phase III trial underway
Choosing quality of life
Aims to prove GATA6 can provide important information in neoadjuvant settings
A rapid response helps everything fall into place
Trying a drug approved for another disease
Now open to those with a first-degree relative with pancreatic cancer
Taking on PNET with all I have
A different kind of ablation for stage III pancreatic cancer
Making choices for my survival
Using irreversible electroporation to make chemotherapy more effective
Research focused on HuR and IDH1 provides new insights
Coaching the coach through a serious illness
COMBAT trial using triple therapies shows promising results
Chicken Enchiladas and Pancreatic Cancer
Combining a new drug with standard treatment
PRECEDE Consortium and Project Purple join forces
Family history of the disease leads me to early detection trial
Exploiting vitamin C’s ability to disrupt cancer metabolism
Different doctors at different locations make an effective treatment plan
Combining an engineered antibody and an anticancer agent to specifically kill tumor cells
Second-round Challenge Grant funding to develop personalized vaccines
BRCA2 mutation and a family history of cancer
Treatments targeted to tumor molecular profile increase survival
First steps in pancreatic cancer treatment
Finding another way to slow or stop the spread of the cancer
Four teams awarded second-round funding
Lessons for finding good treatment options
Tumor treating fields may prove beneficial in locally advanced pancreatic cancer
Two bouts of pancreatic cancer but still optimistic
Adding two types of immunotherapy to chemotherapy
Dana-Farber team researching ways to make targeted therapy more effective
Making quilts to comfort patients and raise money for research
Targeting RNA, the work order of a cell
Researching, reading, and making choices after genetic testing
Using a washing solution to check the spread of cancer cells
Why master regulators matter
Helping others through
Understanding the clinical trials process
Recovering from stage IV pancreatic cancer
Trying a combination across cancers
Getting the most from radiation treatment
Continue with maintenance chemotherapy or take a break?
Small progress lays groundwork for the future
Grateful for a second opinion
Looking for a better presurgical treatment
Discovering a new contributor to disease development
Facing ongoing treatment for PNET
A new study may bring pain relief to more
Rare gene fusion found
Combining a new type of radiation treatment with chemotherapy
Autopsy samples provide more information about the disease
Moving quickly into treatment after a pancreatic cancer diagnosis
The importance of learning about familial mutations
Working with research centers for the latest treatments
Trying to find a method for diagnosing pancreatic cancer at an earlier stage
Stopping a communication breakdown in cells
Petitioning my HMO for the doctors with more experience
Targeting pancreatic cancer metastases
Making a treatment plan and then quickly changing it
Getting directly to the tumor may make a difference
CompCyst can help identify potential cancers
Fantasy sports are a helpful distraction during treatment
Immunotherapy trial with a promising target
Facing treatment three times
Comparing two treatment protocols
Mutations make a difference in treatment options
Not giving in to stage IV pancreatic cancer
Status changes in diabetes patients can indicate cancer
Great response to chemotherapy makes surgery possible
Trying to improve treatment for patients who cannot have surgery
Trying combinations to make immunotherapy work for pancreatic cancer
Giving back to the pancreatic cancer community after treatment
The latest research suggests depression may be an early warning sign of pancreatic cancer
Looking for a treatment plan
Working against the KRAS mutation
Cooperation and collaboration to benefit patients
Calling on my coaching skills to get through treatment
Learning more about inherited mutations
Learning to stay positive with a difficult disease
A combination to better slow or stop tumor growth
New treatment options for some patients
The value of genetic testing— finding a BRCA mutation
Seeking a way to reduce treatment-related hospitalizations
A clinical trial instead of standard treatment alone
Adding a new drug to standard treatment
Chemotherapy responses vary among populations
Researching and traveling for treatments
A possible predictor for longer survival
A surprising find in surgery
A combination of therapies to stimulate the immune system
Understanding the relationship between metabolism and survival
Educating myself to make the best treatment choices
Two targets get for a better result for patients
Beating one challenge leads to taking on another
Trying an immunotherapy drug that works on similar tumor types
BRCA1/2 mutations point the way to a potential treatment
A blocked bile duct leads to diagnosis
Finding another route to effective treatments
Long road of testing finally leads to a diagnosis
Combatting a condition affecting patients with advanced pancreatic cancer
Precision radiation for pancreatic tumors
Odd pain leads to pancreatic neuroendocrine tumor diagnosis
Bacteria in the pancreas may impact immunotherapy
Qualifying for an immunotherapy drug
A drug for bone marrow and blood diseases that may help pancreatic cancer
A new study results in recommendation changes
Quality of life includes increasing my time with my family
Targeted therapy now available
Genetic testing changed my treatment plan
Comparing combinations to battle advanced pancreatic cancer
Treatment gains and next steps
The right treatment made me believe I could survive
A rare (at the time) operation leads to long-term survival
Two clinical trials take on the immune system
Combining two different approaches to slow tumor growth
Participating in trials helps everyone
Focusing on a receptor associated with chemotherapy resistance
A family history leads me to push for a diagnosis
Assessing risks and treatment options for patients and families
A former basketball coach shares his thoughts
Trying treatments that are effective on other cancers
New study aims to fill treatment gap
Traveling to Boston gets me into a research study
A comparison of possible early detection methods
Targeting a tumor marker
Treatment leads to long-term survival
Majority of states and patients approve
A serious medical crisis uncovered an even more serious cause
Producing an immune response to a patient’s tumor
A step-by-step plan to combat my pancreatic cancer
A new version may improve on an older drug
Innovative treatment makes all the difference
Using targeted radiation during chemotherapy
Why immunotherapy has had limited success against pancreatic cancer
A vow to fight hard for my young family
Another approach to finding pancreatic cancer earlier
Learning about the disease to make educated treatment choices
A different type of immunotherapy
Finding ways for pancreatic cancer patients to live longer
Not even Hurricane Harvey can stop my battle
Adding vitamin D to a drug combination
A different treatment plan for some patients
Resection or NanoKnife as the goal
Exploring a treatment targeted to carriers of certain mutations
Taking the reins to get into a clinical trial
Increasing the possibility of finding pancreatic cancer at its earliest stages
Chemotherapy, a common high blood pressure medication, immunotherapy, and radiation under study
A unique treatment plan works for me
Adding to a combination that includes an antimalarial drug
An active life with pancreatic cancer
Making radiation possible at higher doses
These “mini-tumors” may help personalize pancreatic cancer treatment
An opportunity for a clinical trial from a bad diagnosis
A possible reason why cancer spreads after surgery removes a tumor
Vague symptoms add up to pancreatic cancer
A new drug for pancreatic cancer patients who qualify for surgery
Two types of immunotherapy team up to tackle pancreatic cancer
My doctor followed up on vague symptoms
Changing the outer layer of cancer cells
Focusing on those who defied the odds in all fields
A possible new way to stop PNETs
Learning more about familial pancreatic cancer
A mutation means close monitoring for other cancers
Weight loss alerts family doctor at annual physical
Increasing the possibility of surgery to increase the possibility of survival
New treatments plus an experienced surgical team change the picture
A chemotherapy regimen designed for me
Molecular profiling can direct early stages of treatment
Breaking through the fibrous layer to possibly make the cancer removable
My doctor wanted to look further because of my history of gastrointestinal problems
A noninvasive method for catching cancer earlier
Seeking a more effective treatment for pancreatic neuroendocrine tumors
Triathlon training helps me feel like myself despite having pancreatic cancer
Research into understanding the relationship between stroma and tumors
A treatment to decrease the likelihood of remaining cancer cells in tissue margins after tumor removal surgery
Intuition leads to early diagnosis
Boosting the odds for successful immunotherapy
A combination to arrest the spread of pancreatic cancer
A doctor with a more positive attitude helps me through treatment
Making stenting more effective at unblocking bile ducts
Sharing my cancer journey as I travel brings the support of many
Comparing two regimens that combine different treatments
Choosing the treatment to make my life the most comfortable
Explaining the different mutations
Attacking the proteins that encourage cancer growth
Surgery for benign IPMN tumor leads to monitoring for pancreatic cancer
Learning to reprogram the pancreatic tumor microenvironment
A trial for advanced pancreatic and colorectal cancers
Learning to take charge of my treatment
The benefits of participating in a clinical trial
A new class of drug to work with existing treatment
Looking for a clinical trial
A look at the status of immunotherapy
A multi-pronged approach to making tumors removable
I was screened annually because of a family history of pancreatic cancer
More genetic information can help bring about early detection tests
Pairing drugs for two different types of cancer
Traveling to get the treatment I needed
An old school risk assessment tool makes a comeback
A multipronged attack to stop a pancreatic tumor
Trying different treatments to battle recurrent cancer
A way to help doctors identify early detection and screening options
Making platinum compounds work better
Chemotherapy, radiation, and surgery have given me more time
Ongoing phase III trial hopes to confirm early findings
Testing an additional drug for increased response
Staying informed about treatment options helps me battle recurrences
Simple blood test can pick up disease at various stages
Studying the safety of an immunotherapy and vitamin D combination
My quality of life is very important
A clinical trial for my future and future patients
Screening and early diagnosis remain beneficial
A new drug may work where previous chemotherapy has not
A Whipple and a clinical trial gave my husband a chance at survival
A much-needed option for some pancreatic cancer patients with advanced disease
Adding an experimental drug to standard treatment
Good health is allowing me to support others
Comparing drugs and growing organoids
Testing a PARP inhibitor as an alternative to platinum-based chemotherapy
Blocking the molecules necessary for pancreatic cancer growth
A shocking diagnosis leads quickly to treatment
Stopping cancer cells from regrowing
BRCA-like genetic mutation determines treatments
Ongoing clinical trials investigating treatment with targeted high-dose radiation
Using tumor genetics to determine treatment
My third act as a pancreatic cancer activist
Although the jury is still out, more research is showing a potential link.
A diagnosis, then a treatment plan
A growing number of oncologists are extending survival rates using low-dose combination chemotherapy
Trying a PARP inhibitor, which is known to be more effective in BRCA carriers
Testing positive for the BRCA-2 mutation leads to a different treatment
Changing hospitals leads to a change in treatment
A new type of clinical trial
A new clinical trial to test what was found in the lab
I took a chance as the first patient on this trial
A two-phase trial compares the effectiveness of different drugs and radiation in cancer that has been surgically removed
Vitamin may make it easier for chemotherapy to reach the tumor