However, ongoing clinical trials are investigating combination treatments with standard chemotherapies to improve outcomes.
For example, the standard frontline regimen nab-paclitaxel (Abraxane) plus gemcitabine is being studied in combination with the monoclonal antibody vantictumab (OMP-18R5) in a phase Ib dose-escalation study for patients with previously untreated stage IV pancreatic cancer (NCT02005315). Safety and maximum-tolerated dose are the study’s primary outcome measures. Read more . . .