Pancreas and Colon Tumors Reprogram the Liver, Causing Wasting and Short-Circuiting Body’s Immune Response

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One of the worst cruelties of lethal cancer is the phenomenon called wasting, or in medical terms, cachexia (pronounced ka-CHEX-ia), in which a patient seems literally to diminish in bodily terms as the cancer ravages one or more internal organs.

Today, a team at Cancer Research UK Cambridge Institute, led by Professor Douglas Fearon, M.D., of Cold Spring Harbor Laboratory in New York and a Distinguished Scholar of the Lustgarten Foundation, publishes in Cell Metabolism results of experiments showing that tumors interfere with the patient’s ability to cope with  wasting and may even impair their ability to respond to immunotherapy. Read more . . .

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