Ambry Genetics and Nationwide Collaborators Begin Prospective Multi-Site Study to Identify Hereditary Pancreatic Cancer

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Ambry Genetics (Ambry) and its collaborators at Beth Israel Deaconess Medical Center (Boston, MA), University of Pittsburgh (Pittsburgh, PA), and HonorHealth Research Institute (Scottsdale, AZ) today announce a prospective multi-site research study aimed to determine mutation prevalence, as well as psychological assessment and long-term follow up for treatment and care for pancreatic cancer patients with a hereditary predisposition to the disease.

This study will gather valuable data for an underrepresented group of patients diagnosed with cancer carrying an extremely high mortality rate.

Pancreatic cancer represents 3.1% of all new cancer cases in the U.S., with only 7.7% of people surviving 5 years or more after their diagnosis. Several genetic syndromes caused by inherited gene mutations may pose a risk for pancreatic cancer, leaving an underlying genetic mechanism to be the cause in ~10% of all pancreatic cancer. High risk gene mutations, such as those in the BRCA2 gene, are identified in families presenting with a constellation of tumors (including breast, ovarian, pancreatic cancer) but may go undetected in families with only a clustering of pancreatic tumors or isolated pancreatic cancer cases. Read more . . .

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